USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: G6PD_HUMAN USC-OGP 2-DE database:  G6PD_HUMAN G6PD_HUMAN General information about the entry View entry in simple text format Entry name G6PD_HUMAN Primary accession number P11413 Secondary accession number(s) Q96PQ2 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Glucose-6-phosphate 1-dehydrogenase; Short=G6PD; EC=1.1.1.49;. Gene name Name=G6PD Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0349: pI=6.24; Mw=54664 Cross-references UniProtKB/Swiss-Prot P11413; G6PD_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name G6PD_HUMAN Primary accession number P11413 Secondary accession number(s) D3DWX9 Q16000 Q16765 Q8IU70 Q8IU88 Q8IUA6 Q96PQ2 Sequence was last modified on  January 23, 2007 (version 4) Annotations were last modified on  March 15, 2017 (version 225) Name and origin of the protein Description RecName: Full=Glucose-6-phosphate 1-dehydrogenase; Short=G6PD; EC=1.1.1.49; Gene name Name=G6PD Encoded on Name=G6PD Keywords 3D-structure; Acetylation; Alternative splicing; Carbohydrate metabolism; Complete proteome; Direct protein sequencing; Disease mutation; Glucose metabolism; Hereditary hemolytic anemia; NADP; Oxidoreductase; Phosphoprotein; Polymorphism; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X03674; CAA27309.1; -; mRNA EMBL M65234; AAA63175.1; ALT_INIT; Genomic_DNA EMBL M26749; AAA63175.1; JOINED; Genomic_DNA EMBL M26750; AAA63175.1; JOINED; Genomic_DNA EMBL M65225; AAA63175.1; JOINED; Genomic_DNA EMBL M65226; AAA63175.1; JOINED; Genomic_DNA EMBL M65227; AAA63175.1; JOINED; Genomic_DNA EMBL M65228; AAA63175.1; JOINED; Genomic_DNA EMBL M65229; AAA63175.1; JOINED; Genomic_DNA EMBL M65230; AAA63175.1; JOINED; Genomic_DNA EMBL M65231; AAA63175.1; JOINED; Genomic_DNA EMBL M65233; AAA63175.1; JOINED; Genomic_DNA EMBL M65232; AAA63175.1; JOINED; Genomic_DNA EMBL M21248; AAA52500.1; -; mRNA EMBL M19866; AAA52501.1; -; mRNA EMBL X55448; CAA39089.1; -; Genomic_DNA EMBL L44140; AAA92653.1; -; Genomic_DNA EMBL AF277315; AAL27011.1; -; Genomic_DNA EMBL CH471172; EAW72682.1; -; Genomic_DNA EMBL CH471172; EAW72686.1; -; Genomic_DNA EMBL BC000337; AAH00337.1; -; mRNA EMBL M27940; AAA52504.1; -; mRNA EMBL S58359; AAB26169.1; -; mRNA EMBL X53815; CAA37811.1; -; Genomic_DNA EMBL S64462; AAB20299.1; -; Genomic_DNA EMBL AY158096; AAN76367.1; -; Genomic_DNA EMBL AY158097; AAN76368.1; -; Genomic_DNA EMBL AY158098; AAN76369.1; -; Genomic_DNA EMBL AY158099; AAN76370.1; -; Genomic_DNA EMBL AY158100; AAN76371.1; -; Genomic_DNA EMBL AY158101; AAN76372.1; -; Genomic_DNA EMBL AY158102; AAN76373.1; -; Genomic_DNA EMBL AY158103; AAN76374.1; -; Genomic_DNA EMBL AY158104; AAN76375.1; -; Genomic_DNA EMBL AY158105; AAN76376.1; -; Genomic_DNA EMBL AY158106; AAN76377.1; -; Genomic_DNA EMBL AY158107; AAN76378.1; -; Genomic_DNA EMBL AY158108; AAN76379.1; -; Genomic_DNA EMBL AY158109; AAN76380.1; -; Genomic_DNA EMBL AY158110; AAN76381.1; -; Genomic_DNA EMBL AY158111; AAN76382.1; -; Genomic_DNA EMBL AY158112; AAN76383.1; -; Genomic_DNA EMBL AY158113; AAN76384.1; -; Genomic_DNA EMBL AY158114; AAN76385.1; -; Genomic_DNA EMBL AY158115; AAN76386.1; -; Genomic_DNA EMBL AY158116; AAN76387.1; -; Genomic_DNA EMBL AY158117; AAN76388.1; -; Genomic_DNA EMBL AY158118; AAN76389.1; -; Genomic_DNA EMBL AY158119; AAN76390.1; -; Genomic_DNA EMBL AY158120; AAN76391.1; -; Genomic_DNA EMBL AY158121; AAN76392.1; -; Genomic_DNA EMBL AY158122; AAN76393.1; -; Genomic_DNA EMBL AY158123; AAN76394.1; -; Genomic_DNA EMBL AY158124; AAN76395.1; -; Genomic_DNA EMBL AY158125; AAN76396.1; -; Genomic_DNA EMBL AY158126; AAN76397.1; -; Genomic_DNA EMBL AY158127; AAN76398.1; -; Genomic_DNA EMBL AY158128; AAN76399.1; -; Genomic_DNA EMBL AY158129; AAN76400.1; -; Genomic_DNA EMBL AY158130; AAN76401.1; -; Genomic_DNA EMBL AY158131; AAN76402.1; -; Genomic_DNA EMBL AY158132; AAN76403.1; -; Genomic_DNA EMBL AY158133; AAN76404.1; -; Genomic_DNA EMBL AY158134; AAN76405.1; -; Genomic_DNA EMBL AY158135; AAN76406.1; -; Genomic_DNA EMBL AY158136; AAN76407.1; -; Genomic_DNA EMBL AY158137; AAN76408.1; -; Genomic_DNA EMBL AY158138; AAN76409.1; -; Genomic_DNA EMBL AY158139; AAN76410.1; -; Genomic_DNA EMBL AY158140; AAN76411.1; -; Genomic_DNA EMBL AY158141; AAN76412.1; -; Genomic_DNA EMBL AY158142; AAN76413.1; -; Genomic_DNA EMBL M12996; AAA52499.1; -; mRNA EMBL M23423; AAB59390.1; -; Genomic_DNA CCDS CCDS14756.2; -. [P11413-3]; . CCDS CCDS44023.1; -. [P11413-1]; . PIR A40309; DEHUG6; . RefSeq NP_000393.4; NM_000402.4. [P11413-3]; . RefSeq NP_001035810.1; NM_001042351.2. [P11413-1]; . UniGene Hs.461047; -; . UniGene Hs.684904; -; . PDB 1QKI; X-ray; 3.00 A; A/B/C/D/E/F/G/H=2-515 PDB 2BH9; X-ray; 2.50 A; A=27-515 PDB 2BHL; X-ray; 2.90 A; A/B=28-515 PDBsum 1QKI; -; . PDBsum 2BH9; -; . PDBsum 2BHL; -; . ProteinModelPortal P11413; -; . SMR P11413; -; . BioGrid 108814; 65; . IntAct P11413; 6; . MINT MINT-4716941; -; . STRING 9606.ENSP00000377192; -; . BindingDB P11413; -; . ChEMBL CHEMBL5347; -; . DrugBank DB05107; 16-Bromoepiandrosterone; . DrugBank DB03461; 2'-Monophosphoadenosine 5'-Diphosphoribose; . DrugBank DB03085; Hydroxyacetic Acid; . iPTMnet P11413; -; . PhosphoSitePlus P11413; -; . SwissPalm P11413; -; . DMDM 116242483; -; . REPRODUCTION-2DPAGE IPI00289800; -; . SWISS-2DPAGE P11413; -; . EPD P11413; -; . MaxQB P11413; -; . PaxDb P11413; -; . PeptideAtlas P11413; -; . PRIDE P11413; -; . DNASU 2539; -; . Ensembl ENST00000369620; ENSP00000358633; ENSG00000160211. [P11413-2]; . Ensembl ENST00000393562; ENSP00000377192; ENSG00000160211. [P11413-3]; . Ensembl ENST00000393564; ENSP00000377194; ENSG00000160211. [P11413-1]; . Ensembl ENST00000621232; ENSP00000483686; ENSG00000160211. [P11413-1]; . GeneID 2539; -; . KEGG hsa:2539; -; . UCSC uc004flx.3; human. [P11413-1]; . CTD 2539; -; . DisGeNET 2539; -; . GeneCards G6PD; -; . HGNC HGNC:4057; G6PD; . HPA HPA000247; -; . HPA HPA000834; -; . MalaCards G6PD; -; . MIM 300908; phenotype; . MIM 305900; gene; . neXtProt NX_P11413; -; . OpenTargets ENSG00000160211; -; . Orphanet 362; Glucose-6-phosphate-dehydrogenase deficiency; . PharmGKB PA28469; -; . eggNOG KOG0563; Eukaryota; . eggNOG COG0364; LUCA; . GeneTree ENSGT00530000063435; -; . HOVERGEN HBG000856; -; . InParanoid P11413; -; . KO K00036; -; . OMA TIFEPIW; -; . OrthoDB EOG091G06FN; -; . PhylomeDB P11413; -; . TreeFam TF300584; -; . BioCyc MetaCyc:HS08467-MONOMER; -; . BRENDA 1.1.1.49; 2681; . Reactome R-HSA-5628897; TP53 Regulates Metabolic Genes; . Reactome R-HSA-71336; Pentose phosphate pathway (hexose monophosphate shunt); . SABIO-RK P11413; -; . SIGNOR P11413; -; . UniPathway UPA00115; UER00408; . ChiTaRS G6PD; human; . EvolutionaryTrace P11413; -; . GeneWiki Glucose-6-phosphate_dehydrogenase; -; . GenomeRNAi 2539; -; . PRO PR:P11413; -; . Proteomes UP000005640; Chromosome X; . Bgee ENSG00000160211; -; . CleanEx HS_G6PD; -; . ExpressionAtlas P11413; baseline and differential; . Genevisible P11413; HS; . GO GO:0005737; C:cytoplasm; IDA:LIFEdb; . GO GO:0009898; C:cytoplasmic side of plasma membrane; IDA:BHF-UCL; . GO GO:0005829; C:cytosol; IDA:BHF-UCL; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005634; C:nucleus; IEA:Ensembl; . GO GO:0005536; F:glucose binding; IDA:BHF-UCL; . GO GO:0004345; F:glucose-6-phosphate dehydrogenase activity; IDA:UniProtKB; . GO GO:0042802; F:identical protein binding; IPI:IntAct; . GO GO:0050661; F:NADP binding; IDA:BHF-UCL; . GO GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL; . GO GO:0034599; P:cellular response to oxidative stress; IMP:BHF-UCL; . GO GO:0006695; P:cholesterol biosynthetic process; IMP:BHF-UCL; . GO GO:0043249; P:erythrocyte maturation; IMP:BHF-UCL; . GO GO:0051156; P:glucose 6-phosphate metabolic process; IDA:UniProtKB; . GO GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW; . GO GO:0006749; P:glutathione metabolic process; IMP:BHF-UCL; . GO GO:0006629; P:lipid metabolic process; TAS:BHF-UCL; . GO GO:0006739; P:NADP metabolic process; IDA:UniProtKB; . GO GO:0006740; P:NADPH regeneration; IMP:BHF-UCL; . GO GO:0061052; P:negative regulation of cell growth involved in cardiac muscle cell development; IEA:Ensembl; . GO GO:0010734; P:negative regulation of protein glutathionylation; IMP:BHF-UCL; . GO GO:2000378; P:negative regulation of reactive oxygen species metabolic process; IEA:Ensembl; . GO GO:0055114; P:oxidation-reduction process; IMP:BHF-UCL; . GO GO:0019322; P:pentose biosynthetic process; IDA:BHF-UCL; . GO GO:0006098; P:pentose-phosphate shunt; IDA:BHF-UCL; . GO GO:0009051; P:pentose-phosphate shunt; oxidative branch; IMP:BHF-UCL GO GO:1904879; P:positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel; IEA:Ensembl; . GO GO:0043523; P:regulation of neuron apoptotic process; IEA:Ensembl; . GO GO:0045471; P:response to ethanol; IEA:Ensembl; . GO GO:0032094; P:response to food; IEA:Ensembl; . GO GO:0010041; P:response to iron(III) ion; IEA:Ensembl; . GO GO:0014070; P:response to organic cyclic compound; IEA:Ensembl; . GO GO:0046390; P:ribose phosphate biosynthetic process; IMP:BHF-UCL; . GO GO:0021762; P:substantia nigra development; IEP:UniProtKB; . Gene3D 3.40.50.720; -; 1; . HAMAP MF_00966; G6PD; 1; . InterPro IPR001282; G6P_DH; . InterPro IPR019796; G6P_DH_AS; . InterPro IPR022675; G6P_DH_C; . InterPro IPR022674; G6P_DH_NAD-bd; . InterPro IPR016040; NAD(P)-bd_dom; . PANTHER PTHR23429; PTHR23429; 1; . Pfam PF02781; G6PD_C; 1; . Pfam PF00479; G6PD_N; 1; . PIRSF PIRSF000110; G6PD; 1; . PRINTS PR00079; G6PDHDRGNASE; . SUPFAM SSF51735; SSF51735; 1; . TIGRFAMs TIGR00871; zwf; 1; . PROSITE PS00069; G6P_DEHYDROGENASE; 1; .

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